Endocrine Abstracts

Case Presentation: A 35-year-old Caucasian male presented to our endocrine clinic with a right pituitary lesion. This was found incidentally on MRI nine months previously after admission with head injury. He was asymptomatic apart from intermittent pain in his left wrist and right knee. He has a history of epilepsy. He was on paracetamol for analgesia, levetiracetam for epilepsy, and was not on any oral, topical, inhaled or injectable steroids. On assessment, he had central ob...

Whilst bariatric surgery is the most effective therapy for idiopathic morbid obesity in adults, little is known about its effectiveness in patients with monogenic obesity syndromes. We report 5-year outcome of gastric bypass surgery in a young man with severe super-obesity associated with melanocortin four receptor (MC4R) mutation.A 22-year-old male with a weight of 221.6 kg and BMI 76.7 kg/m2 was referred to our centre for bariatric surgery. ...

Case Presentation: A 69-year-old female was found unconscious on the floor at her home. She was unable to provide a reliable history due to a GCS of 8. On examination there were no Cushingoid features and normal BMI (20 kg/m2). She was previously fit and well with no significant history. Investigations revealed a hyperosmolar metabolic acidosis (pH 6.9) with a high serum sodium (174 mmol/l) and high glucose (70.5 mmol/l). Chest X-ray revealed left middle zone consol...

Introduction: Hypercalcaemia in pregnancy is an uncommon event that can cause major maternal morbidity and/or foetal morbidity and mortality. We present a case report and discuss management.Case: A 34-year-old woman was seen initially in endocrinology clinic with primary hyperparathyroidism. A neck ultrasound scan did not identify a parathyroid adenoma, but parathyroid MIBI scan suggested a left inferior parath...

Background: Whilst bariatric surgery is cost effective in the management of severe or complex obesity, successful outcomes necessitate specialist multidisciplinary pre-operative and post-operative care. The report by the National Confidential Enquiry into Patient Outcome and Death (NCEPOD), Too Lean a Service? A review of the care of patients who underwent bariatric surgery (2012) made critical recommendations for the process of care.Aims: To as...

Background: Bariatric surgery is the most successful treatment for patients with severe and complex obesity.Aims: To assess clinical outcomes after bariatric surgery in a specialist centre.Setting: Specialist weight management service in a university teaching hospital.Methods: We performed an observational analysis of clinical outcomes for patients who underwent bariatric surgery during the period 31st</...